Strasbourg: Getting the best from your structural data: beyond black boxes

The goal is that the participants improve their theoretical background and gain hands-on experience in the structure determination of “difficult macromolecules” by singlecrystal X-ray crystallography.

Objectives: The course is intended primarily for post-doctoral researchers and Ph.D. students in structural biology. The goal is that the participants improve their theoretical background and gain hands-on experience in the structure determination of “difficult macromolecules” by single crystal X-ray crystallography. The course will cover state-of-the-art methodology for data processing with emphasis on integration of different methods to solve structures of macromolecular complexes and ‘difficult’ targets. More precisely, the course will address two aspects:


- X-ray diffraction; data processing (from frames to deposited model)
- Integration of X-ray crystallography, Cryo-Electron Microscopy and Small Angle Xray scattering in structural biology