Webminar: Pushing the boundaries in biomolecular interaction analysis with the Creoptix WAVEsystem

Summary: Grating-coupled interferometry (GCI) is surface-based, label-free biosensing technology that offers the highest sensitivity and crude sample robustness over a broad range of applications.
The Creoptix WAVEsystem combines the enhanced sensitivity of GCI technology with an innovative, fast-transition fluidics architecture and no-clog WAVEchips. A wide range of molecules can be immobilized using various chemistries or capturing techniques, while remaining compatible with crude samples or complex matrices. This enables a broad range of applications including fragment-based screening and kinetic analysis of small molecules, protein-protein, protein-peptide, antibody-antigen, and nucleic acid interactions.
The Creoptix WAVEsystem offers a new and unique way of measuring kinetics. Instead of relying on a titration series, waveRAPID (Repeated Analyte Pulses of Increasing Duration) injects a single concentration, pulsing the sample over the sensing surface at increasing durations. Thanks to that, kinetics can be derived from a single well speeding up screening or binding characterization measurements.